March 29, 2011 - Family Tree DNA posted the results of the lastest 37-marker DNA sample this evening. From it we can infer with high confidence, that we know the entire DNA profile for George Pemberton, born about 1685 in Cheshire, England, and emigrated to the Virginia Colony in 1710. This same DNA profile was carried down three generations through his son Isaiah, his grandson Isaiah, and his great grandson Robert. How do we do that?
We have three 37-marker samples from his progeny. Two of the samples have a documented common ancestor in Robert L Pemberton, b. 20 Jan 1788, in South Carolina. This Robert and the third sample have a common ancestor in this George Pemberton of Cheshire. Each of the three samples has one marker different from the other two and these three are located at different points along the genome. So using the statistical mode, we infer the result. To make this a bit clearer, here are the specific details:
The three markers and their respective modes (two out of three sample) values are: DYS447=24, DSY464b=16, and CDYb=40. The other 34 markers all have the same value in all three samples. We will post the entire profile in the Pemberton DNA Project page tomorrow. Meanwhile, here is a chart showing the transmission of George's DNA and the mutations that have occurred. Here is the full article on Pemberton DNA results.
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